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The evolution of RNA viruses: A population genetics view.

2000

RNA viruses are excellent experimental models for studying evolution under the theoretical framework of population genetics. For a proper justification of this thesis we have introduced some properties of RNA viruses that are relevant for studying evolution. On the other hand, population genetics is a reductionistic theory of evolution. It does not consider or make simplistic assumptions on the transformation laws within and between genotypic and phenotypic spaces. However, such laws are minimized in the case of RNA viruses because the phenotypic space maps onto the genotypic space in a much more linear way than on higher DNA-based organisms. Under experimental conditions, we have tested th…

GeneticsMultidisciplinarybiologyvirusesRNAPopulation geneticsGenetic Variationbiology.organism_classificationBiological EvolutionVirusEffective population sizeVesicular stomatitis virusMolecular evolutionViral evolutionColloquium PaperGenetic variationRNA VirusesProceedings of the National Academy of Sciences of the United States of America
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